Candida Vaginitis: When Opportunism Knocks, the Host Responds

Candida Vaginitis: When Opportunism Knocks, the Host Responds

1 Department of Oral and Craniofacial Biology, Dental School, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America, 2 Department of Prosthodontics, Dental School, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America, 3 Department of Microbiology, Immunology, and Parasitology, School of Medicine, Louisi...

Candida vaginitis.

Candida vaginitis Other than the dermatophytic mycoses, Candida vaginitis is the most common fungal disease in the United Kingdom, described by Morton and Rashid (1977) as a near epidemic. Almost all the known facts about it are enumerative or descriptive and little is known of the factors affecting the pathogenesis, recrudescence, or recurrence of the mycosis. The facts do not disclose the psy...

Mortal outcomes when opportunity knocks.

A murine model of Candida glabrata vaginitis.

Vaginal Candida glabrata infections have increased significantly in recent years and are particularly common in women with uncontrolled diabetes mellitus. Efforts to understand the pathogenesis and treatment of this infection have been hindered by the lack of experimental animal models. Before onset of hyperglycemia, nonobese diabetic (NOD) mice inoculated intravaginally with clinical C. glabra...

Studies of Immune Responses in Candida vaginitis

The widespread occurrence of vaginal candidiasis and the development of resistance against anti-fungal agents has stimulated interest in understanding the pathogenesis of this disease. The aim of our work was to characterize, in an animal model of vaginal candidiasis, the mechanisms that play a role in the induction of mucosal immunity against C. albicans and the interaction between innate and ...